MGF (Mechano Growth Factor)

Peptide · IGF-1 splice variant · 24 amino acids

Half-life

~5-7min

After administration

Delivery Method

IM injection

Route of administration

Storage (Lyophilised)

12-24 months

2–8°C

Storage (Reconstituted)

2–4 weeks

Refrigerate at 2-8C

Known For

Splice variant of IGF-1 released locally by damaged muscle tissue. Promotes muscle satellite cell activation and repair. Very short half-life (~5-7 minutes).

Mechanism of Action

Splice variant of IGF-1 produced by damaged muscle tissue. Proposed to activate satellite cells for localised muscle repair.

Body vs. External Supply

🟡 Natural/Topping Up

Typical Research Dosage

100-200mcg IM bilaterally into trained muscle, immediately post-workout. Due to short half-life, timing is critical.

Vial Duration Guide

2mg vial at 200mcg/dose = 10 doses.

Common Side Effects

Injection site pain, limited safety data

Drug Interactions

Unknown — very limited research

Reversibility

Fully reversible — extremely short acting

Storage Requirements

Reconstituted: 2-8°C, 7-14 days (unstable)

State	Condition	Duration
Lyophilised (sealed)	2–8°C	12-24 months
Reconstituted	2-8C	2–4 weeks

Reconstitution Note

Reconstitute with bacteriostatic water (BAC water). Do not shake vigorously -- swirl gently to dissolve. Inject BAC water slowly down the side of the vial to avoid denaturing the peptide.

Video Resources

MGF (Mechano Growth Factor) discussed by researchers & practitioners

Independent educational content from researchers, clinicians, and science communicators. Not affiliated with Pepnerd — provided as supplementary reading.

Educational resources only. The videos above are independent third-party content from researchers, clinicians, and science communicators. Pepnerd is not affiliated with any of these creators and does not endorse or make any claims based on their content. All products are sold strictly for in-vitro scientific research.

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Quick Reference

Half-life	~5-7 minutes (extremely short — limits utility)
Delivery	IM injection
Typical dose	100-200mcg
Storage (lyoph.)	2–8°C
Storage (recon.)	2–4 weeks
Endogenous?	Natural/Topping Up
Suppression	None known
WADA	Prohibited (S2)
FDA status	Category 2 (2023)