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CognitiveImmuneIn StockSubQ injection

Selank

Heptapeptide · Tuftsin analogue · 7 amino acids
Half-life
~3-5min
After administration
Delivery Method
SubQ injection
Route of administration
Storage (Lyophilised)
12-24 months
room temp
Storage (Reconstituted)
2–4 weeks
Refrigerate at 2-8C

Known For

Nootropic and anxiolytic peptide. Synthetic analogue of the immunomodulatory peptide tuftsin. Reduces anxiety without sedation, improves memory and focus, and modulates immune function. Popular in Russian clinical practice.

Mechanism of Action

Synthetic analog of tuftsin (immune peptide). Anxiolytic (anti-anxiety) + nootropic (cognitive enhancement). Modulates GABA, serotonin, dopamine. Approved in Russia.

Body vs. External Supply

🔴 Exogenous (replaces natural)

Brand / Trade Names

Selank® (approved in Russia) Manufacturer: Institute of Molecular Genetics (Russia) Not available as pharmaceutical outside Russia

Typical Research Dosage

Intranasal: 200-400mcg 2-3x daily. SubQ: 100-300mcg daily.

Vial Duration Guide

5mg vial at 400mcg/day = ~12.5 days. 10mg = ~25 days.

Recommended Vial Size

★ 5mg vials — RECOMMENDED At 400mcg/day, 5mg = ~12.5 days ✓. Selank is fragile (2-4 wk shelf life). 5mg ensures maximum potency. 10mg = 25 days — borderline.

Time to Effects

EARLY: 15-30 minutes FULL: 2-4 weeks First dose: Anxiolytic effects can be felt within 15-30 minutes of intranasal administration. Subtle calm, improved focus without sedation. Week 1-2: Anxiety reduction becomes more consistent. Improved stress tolerance. Better focus and mental clarity. Week 2-4: Full nootropic and anxiolytic effect. Immune modulation benefits. Stabilised mood. One of the faster-acting nootropic peptides. Minimum commitment: 2-4 weeks for sustained cognitive benefits. Many feel the anti-anxiety effect from dose one.

Contraindications & Do Not Combine

No strict contraindications with other peptides on this list.

Common Side Effects

Nasal irritation, fatigue (rare), slight sedation at higher doses. Generally very well tolerated.

Drug Interactions

Benzodiazepines (additive but different mechanism — not cross-tolerant), SSRIs, alcohol

Reversibility

Fully reversible — no physical dependence reported (unlike benzodiazepines). No withdrawal symptoms.

Key Peer-Reviewed References

All studies are published in indexed journals unless otherwise noted.

• Zozulya et al. (2001) Bull Exp Biol Med 131:564-6 — Anxiolytic effects • Seredenin et al. (2002) Bull Exp Biol Med 133:143-5 • Approved in Russia as anxiolytic nasal spray • NOT FDA APPROVED in USA/EU/Australia • Modified tuftsin analog — limited Western clinical data

Research Disclaimer

Almost all data is preclinical (animal or in-vitro). No large-scale randomised controlled human trials are available for most compounds on this catalogue. This information is provided for research reference only.

Storage Requirements

Nasal solution: 2-8°C, 14-30 days. Lyophilized: room temp.
State Condition Duration
Lyophilised (sealed) room temp 12-24 months
Reconstituted 2-8C 2–4 weeks

Reconstitution Note

Reconstitute with bacteriostatic water (BAC water). Do not shake vigorously -- swirl gently to dissolve. Inject BAC water slowly down the side of the vial to avoid denaturing the peptide.

Video Resources

Selank discussed by researchers & practitioners

Independent educational content from researchers, clinicians, and science communicators. Not affiliated with Pepnerd — provided as supplementary reading.

Educational resources only. The videos above are independent third-party content from researchers, clinicians, and science communicators. Pepnerd is not affiliated with any of these creators and does not endorse or make any claims based on their content. All products are sold strictly for in-vitro scientific research.

Selank
Selank
98% Purity . HPLC Verified
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Quick Reference
Half-life ~3-5 minutes (intranasal — acts rapidly on brain)
Delivery SubQ injection
Typical dose 200-400mcg
Storage (lyoph.) room temp
Storage (recon.) 2–4 weeks
Endogenous? Exogenous (replaces natural)
Suppression None known
WADA Not listed
FDA status Not reviewed (Russian research)