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Ipamorelin

Pentapeptide · Selective GHS-R agonist · 5 amino acids
Half-life
~2h
After administration
Delivery Method
SubQ injection
Route of administration
Storage (Lyophilised)
12-24 months
2–8°C
Storage (Reconstituted)
4–6 weeks
Refrigerate at 2-8C

Known For

Growth hormone releasing peptide (GHRP). The 'cleanest' GHRP — minimal cortisol and prolactin increase unlike GHRP-2/6. Selective GH release. Great for sleep quality, recovery, and anti-aging.

Mechanism of Action

Selective GH secretagogue (ghrelin mimetic) — stimulates pituitary to release GH via ghrelin pathway WITHOUT stimulating cortisol, prolactin, or hunger (unlike GHRP-6).

Body vs. External Supply

🟢 Secretagogue (stimulates natural)

Brand / Trade Names

No pharmaceutical brand Research peptide only FDA Category 2 (2023)

Typical Research Dosage

100-300mcg per injection, 2-3x daily. Must be fasted.

Vial Duration Guide

5mg vial at 300mcg/day = ~17 days. 10mg at 300mcg/day = ~33 days.

Recommended Vial Size

★ 5mg vials At 300mcg/day, 5mg = ~17 days ✓. 10mg = 33 days ✓. 5mg for maximum freshness.

Time to Effects

EARLY: 2-4 weeks FULL: 8-12 weeks Week 1-2: Improved sleep, especially with bedtime dose. Week 2-4: Better recovery, subtle energy increase. Week 8-12: Body composition improvements. Much less effective alone — pair with CJC-1295 NO DAC for proper results. Minimum commitment: 8 weeks.

Contraindications & Do Not Combine

• Do NOT combine with exogenous HGH (pituitary suppression makes Ipa ineffective) • Can combine with ONE other GHRP if needed, but avoid stacking multiple GHRPs (diminishing returns, increased side effects)

Common Side Effects

Head rush/flushing (10%), headache, mild transient hunger (less than GHRP-6), injection site reaction

Drug Interactions

Somatostatin analogs (antagonize). Otherwise minimal interactions — cleanest side effect profile of all GHSPs.

Reversibility

🟢 Fully reversible — body returns to baseline within days

Key Peer-Reviewed References

All studies are published in indexed journals unless otherwise noted.

• Raun et al. (1998) Eur J Endocrinol 139(5):552-61 — First selective GHSP characterization • Johansen et al. (1999) Growth Horm IGF Res 9(2):106-13 — Bone growth in rats • NOT FDA APPROVED • FDA Category 2 bulk drug substance (2023) • Well-characterized selectivity profile (minimal cortisol/prolactin effects)

Research Disclaimer

Almost all data is preclinical (animal or in-vitro). No large-scale randomised controlled human trials are available for most compounds on this catalogue. This information is provided for research reference only.

Storage Requirements

Reconstituted: 2-8°C, 14-21 days
State Condition Duration
Lyophilised (sealed) 2–8°C 12-24 months
Reconstituted 2-8C 4–6 weeks

Reconstitution Note

Reconstitute with bacteriostatic water (BAC water). Do not shake vigorously -- swirl gently to dissolve. Inject BAC water slowly down the side of the vial to avoid denaturing the peptide.

Video Resources

Ipamorelin discussed by researchers & practitioners

Independent educational content from researchers, clinicians, and science communicators. Not affiliated with Pepnerd — provided as supplementary reading.

Educational resources only. The videos above are independent third-party content from researchers, clinicians, and science communicators. Pepnerd is not affiliated with any of these creators and does not endorse or make any claims based on their content. All products are sold strictly for in-vitro scientific research.

Ipamorelin
Ipamorelin
98% Purity . HPLC Verified
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$40.00 per vial
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Quick Reference
Half-life ~2 hours
Delivery SubQ injection
Typical dose 100-300mcg
Storage (lyoph.) 2–8°C
Storage (recon.) 4–6 weeks
Endogenous? Secretagogue (stimulates natural)
Suppression None (selective GH pulse)
WADA Prohibited (S2)
FDA status Category 2 (2023)