SNAP-8

Octapeptide · SNAP-25 N-terminus analogue · 8 amino acids

Half-life

~2-4h (topical)

After administration

Delivery Method

Topical cream/serum

Route of administration

Storage (Lyophilised)

12-24 months

Room temp

Storage (Reconstituted)

4–6 weeks

Refrigerate at 2-8C

Known For

Anti-wrinkle peptide. Works similarly to Botox by inhibiting SNARE complex formation, reducing muscle contraction that causes expression lines. Topical or injectable. Primarily cosmetic.

Mechanism of Action

Acetyl octapeptide-3 — competes with SNAP-25 in SNARE complex to reduce muscle contraction signals. 'Topical Botox' — relaxes expression lines.

Body vs. External Supply

🔴 Exogenous (replaces natural)

Brand / Trade Names

Marketed in skincare as: Snap-8™ (Lipotec/Lubrizol) Argireline® is related (Acetyl hexapeptide-3) Cosmeceutical — not injectable

Typical Research Dosage

Topical: apply to wrinkle areas. Injectable: 50-100mcg SubQ to target areas. Limited dosing data for injection.

Vial Duration Guide

10mg vial: long-lasting at typical doses. Primarily used topically mixed into serums.

Recommended Vial Size

★ 10mg (only size) Primarily topical use in serums. Injectable at 100mcg/day = 100 days ⚠️. Shelf life less of a concern for topical preparations.

Time to Effects

EARLY: 2-4 weeks (topical) FULL: 8-12 weeks Topical application: Week 2-4: Subtle softening of expression lines in application area. Week 4-8: Noticeable reduction in fine lines and wrinkles. Week 8-12: Maximum effect — significant wrinkle reduction in target areas. Effects are temporary — similar to Botox but milder. Continuous use required to maintain results.

Contraindications & Do Not Combine

No strict contraindications with other peptides on this list.

Common Side Effects

Skin irritation (rare), minimal systemic absorption

Drug Interactions

None significant (topical only, minimal systemic absorption)

Reversibility

Fully reversible — muscle function returns when discontinued

Key Peer-Reviewed References

All studies are published in indexed journals unless otherwise noted.

• Lipotec/Lubrizol proprietary research — Acetyl octapeptide-3 • Cosmetic use only — topical 'Botox alternative' • Limited peer-reviewed independent research • NOT FDA APPROVED • Primarily cosmeceutical industry data

Research Disclaimer

Almost all data is preclinical (animal or in-vitro). No large-scale randomised controlled human trials are available for most compounds on this catalogue. This information is provided for research reference only.

Storage Requirements

Per product label — typically 6-12 months. Store away from light/heat.

State	Condition	Duration
Lyophilised (sealed)	Room temp	12-24 months
Reconstituted	2-8C	4–6 weeks

Reconstitution Note

Reconstitute with bacteriostatic water (BAC water). Do not shake vigorously -- swirl gently to dissolve. Inject BAC water slowly down the side of the vial to avoid denaturing the peptide.

Select Vial Size

$45.00 per vial

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Quick Reference

Half-life	~Hours (topical compound, not injectable)
Delivery	Topical cream/serum
Typical dose	50-100mcg
Storage (lyoph.)	Room temp
Storage (recon.)	4–6 weeks
Endogenous?	Exogenous (replaces natural)
Suppression	None
WADA	Not listed
FDA status	Not reviewed (cosmetic)