Oxytocin Acetate

Nonapeptide · Neurohypophysial hormone · 9 amino acids

Half-life

~3-5min

After administration

Delivery Method

SubQ injection

Route of administration

Storage (Lyophilised)

12-24 months

2–8°C

Storage (Reconstituted)

4–6 weeks

Refrigerate at 2-8C

Known For

The 'bonding hormone'. Promotes social bonding, trust, anxiety reduction, and intimacy. Also has roles in wound healing, anti-inflammation, and stress reduction. Nasal spray is the most common delivery.

Mechanism of Action

"Love hormone" — naturally produced during bonding, birth, breastfeeding. Promotes social bonding, trust, uterine contraction, milk ejection.

Body vs. External Supply

🔴 Exogenous (replaces natural)

Brand / Trade Names

Pitocin® (IV, labor induction) Syntocinon® (nasal spray, some countries) Manufacturer: Various

Typical Research Dosage

Intranasal: 20-40 IU (typically 1-2 sprays per nostril). SubQ: 5-20 IU. Used before social situations or intimacy.

Vial Duration Guide

Dosing in IU varies by concentration. 2mg vial provides many doses at typical intranasal amounts.

Recommended Vial Size

★ 2mg vials Small doses (IU-level). 2mg = many doses. Oxytocin is fragile — smaller vials = fresher. 5 and 10mg risk degradation.

Time to Effects

EARLY: 15-30 minutes FULL: Single dose On-demand compound similar to PT-141. 15-30 min post-administration: Increased feelings of warmth, bonding, trust, reduced anxiety. Duration: 1-3 hours for acute effects. Intranasal onset is faster (15 min) than SubQ (30 min). Effects are felt from first dose. No loading required. Some report cumulative anxiety-reduction benefits with regular use over 2-4 weeks.

Contraindications & Do Not Combine

⚠️ ABSOLUTE CONTRAINDICATION in pregnancy — oxytocin induces uterine contractions and can cause premature labour No strict contraindications with other peptides on this list.

Common Side Effects

Nausea, headache, intranasal irritation, uterine cramping (women), ⚠️ water intoxication/hyponatremia at high IV doses (Pitocin obstetric use)

Drug Interactions

Prostaglandins (synergistic uterine contraction), SSRIs (may enhance effect), vasopressin analogs

Reversibility

Fully reversible — very short-acting

Key Peer-Reviewed References

All studies are published in indexed journals unless otherwise noted.

• FDA Approved: Pitocin (IV, labor induction) • Kosfeld et al. (2005) Nature 435:673-6 — Intranasal trust/social bonding • MacDonald et al. (2011) Harvard Rev Psychiatry 19:312-28 — Social behavior review • Well-established safety profile for medical use • Off-label intranasal use for social/bonding purposes is less studied

Research Disclaimer

Almost all data is preclinical (animal or in-vitro). No large-scale randomised controlled human trials are available for most compounds on this catalogue. This information is provided for research reference only.

Storage Requirements

Intranasal: 2-8°C, per label. IV: hospital supply chain.

State	Condition	Duration
Lyophilised (sealed)	2–8°C	12-24 months
Reconstituted	2-8C	4–6 weeks

Reconstitution Note

Reconstitute with bacteriostatic water (BAC water). Do not shake vigorously -- swirl gently to dissolve. Inject BAC water slowly down the side of the vial to avoid denaturing the peptide.

Select Vial Size

$30.00 per vial

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Quick Reference

Half-life	~3-5 minutes (IV) \| ~20 minutes (intranasal)
Delivery	SubQ injection
Typical dose	20-40 IU
Storage (lyoph.)	2–8°C
Storage (recon.)	4–6 weeks
Endogenous?	Exogenous (replaces natural)
Suppression	None known
WADA	Not listed
FDA status	Approved (Pitocin)