Metabolic

HGH Fragment 176-191

Peptide fragment · GH C-terminus · 16 amino acids

FDA · CATEGORY 2 (2023)

Half-life

~22 minutes

Very short

minsdays

Route

SubQ injection

Evidence

Preclinical only

Risk

Standard

Overview

Known for

The fat-burning fragment of human growth hormone. Same active sequence as AOD 9604. Stimulates lipolysis without affecting blood sugar or promoting growth.

Mechanism

Synthetic fragment of HGH (amino acids 176-191). Proposed fat-burning portion of HGH without growth effects. Very similar to AOD 9604.

Key facts

Format
Lyophilized powder
Mechanism targets
Classification
Secondary
Supply & nature
Natural / Topping UpNatural
FDA category
Category 2 (2023)

Evidence & standing

Evidence base
Preclinical only
Risk level
Standard
Best studies
4 references
  • Wu et al. (1993) Biochem Biophys Res Commun 190:167-73 — Original characterization of fragment
  • Same research base as AOD 9604 (modified version of this fragment)
  • NO FDA APPROVAL — Research peptide only
  • Primarily animal model studies

Dosage & protocol

Typical dose
250-500mcg/day
Research range
250–500 µg
Cycle
Daily, pre-fasted
Onset
35 days first effects
Full effect
98 days
Half-life
~15-30min
~15-30 minutes
Protocol

250-500mcg/day SubQ, typically split AM/PM. Must be fasted.

Time to effects

EARLY: 4-6 weeks

FULL: 12-16 weeks

Same timeline as AOD 9604 (same active fragment). Subtle fat metabolism effects rather than dramatic changes.

Minimum commitment: 8-12 weeks. Modest standalone results.

Recommended vial
  • 5mg (only size)

At 500mcg/day = 10 days ✓. At 250mcg/day = 20 days ✓. No shelf life issues.

Reference figures only

Dosing reflects published laboratory protocols and is not guidance for use in any living subject.

Safety

Reversibility
Fully Reversible
Side effects

Injection site irritation, headache

Interactions

No significant known interactions

Handle with research caution

No strict contraindications with other peptides on this list.

Storage & handling

Lyophilised
12–24 months
2–8°C
Reconstituted
2–4 weeks
2–8°C

Videos & talks

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