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Sexual healthIn StockSubQ injection

Gonadorelin Acetate

Decapeptide · GnRH sequence · 10 amino acids

Half-life

~2-4min

After administration

Delivery Method

SubQ injection

Route of administration

Storage (Lyophilised)

12-24 months

2–8°C

Storage (Reconstituted)

2–4 weeks

Refrigerate at 2-8C

Known For

Synthetic GnRH (gonadotropin-releasing hormone). Stimulates pituitary to release LH and FSH. Used to maintain or restore fertility and testicular function, especially during TRT. Also used diagnostically.

Mechanism of Action

Identical to endogenous GnRH — signals pituitary to release LH and FSH. Used diagnostically (test pituitary function) and therapeutically (pulsatile for fertility).

Body vs. External Supply

🟢 Secretagogue (stimulates natural)

Brand / Trade Names

Factrel® (diagnostic — discontinued) Lutrepulse® (pulsatile — discontinued) Cystorelin® (veterinary) Widely compounded for TRT protocols

Typical Research Dosage

100-400mcg SubQ 2-3x per week. Some protocols use daily microdoses.

Vial Duration Guide

2mg vial at 200mcg 3x/wk = ~3.3 weeks.

Recommended Vial Size

★ 2mg (only size) At 200mcg 3x/wk, 2mg = ~3.3 weeks ✓. Perfect shelf life fit.

Time to Effects

EARLY: 2-4 weeks FULL: 8-12 weeks Week 1-2: LH/FSH response measurable on blood work. Week 2-4: Testosterone levels stabilising/increasing. Testicular volume maintained or improving. Week 4-8: Hormonal improvements reflected in energy, libido, mood. Week 8-12: Full effect. Fertility parameters improved. For fertility: minimum 3 months. For testosterone support: 6-8 weeks to assess.

Contraindications & Do Not Combine

• Caution combining with HCG (both stimulate LH pathway — monitor estrogen/testosterone ratio to avoid excess stimulation)

Common Side Effects

Flushing, headache, nausea (mild), injection site reaction, allergic reaction (rare)

Drug Interactions

GnRH agonists/antagonists (contraindicated — opposite effects), dopamine agonists, gonadal steroids affect response

Reversibility

🟡 Fully reversible — identical to body's own hormone. Pulsatile administration maintains/restores axis. Continuous administration paradoxically SUPPRESSES (desensitization).

Key Peer-Reviewed References

All studies are published in indexed journals unless otherwise noted.

• Previously FDA Approved as Factrel (1976) — diagnostic GnRH stimulation test • Lutrepulse (pulsatile) for hypothalamic amenorrhea — discontinued • Well-established pharmacology — identical to endogenous GnRH • Used in fertility clinics for decades • Common in TRT protocols to maintain testicular function

Research Disclaimer

Almost all data is preclinical (animal or in-vitro). No large-scale randomised controlled human trials are available for most compounds on this catalogue. This information is provided for research reference only.

Storage Requirements

Reconstituted: 2-8°C, 14 days

State	Condition	Duration
Lyophilised (sealed)	2–8°C	12-24 months
Reconstituted	2-8C	2–4 weeks

Reconstitution Note

Reconstitute with bacteriostatic water (BAC water). Do not shake vigorously -- swirl gently to dissolve. Inject BAC water slowly down the side of the vial to avoid denaturing the peptide.

Video Resources

Gonadorelin Acetate discussed by researchers & practitioners

Independent educational content from researchers, clinicians, and science communicators. Not affiliated with Pepnerd — provided as supplementary reading.

Educational resources only. The videos above are independent third-party content from researchers, clinicians, and science communicators. Pepnerd is not affiliated with any of these creators and does not endorse or make any claims based on their content. All products are sold strictly for in-vitro scientific research.

Select Vial Size

$35.00 per vial

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Quick Reference

Half-life	~2-4 minutes (IV) \| ~20-40 minutes (SubQ)
Delivery	SubQ injection
Typical dose	100-400mcg
Storage (lyoph.)	2–8°C
Storage (recon.)	2–4 weeks
Endogenous?	Secretagogue (stimulates natural)
Suppression	None (stimulates LH/FSH)
WADA	Not listed
FDA status	Approved (Factrel)