Home / Catalogue/ Metabolic/ 5-Amino-1MQ

MetabolicIn StockSubQ injection

5-Amino-1MQ

Small molecule · NNMT inhibitor · Synthetic

Half-life

~2-3h

After administration

Delivery Method

SubQ injection

Route of administration

Storage (Lyophilised)

12-24 months

Room temp (capsule) | Reconstituted: 2-8

Storage (Reconstituted)

4–6 weeks

Refrigerate at 2-8C

Known For

NNMT (nicotinamide N-methyltransferase) inhibitor. Increases cellular energy metabolism and fat burning by boosting NAD+ levels in fat cells. Shrinks fat cells and may prevent new fat cell formation.

Mechanism of Action

NNMT inhibitor — blocks enzyme (nicotinamide N-methyltransferase) that promotes fat storage. May increase NAD+ and boost metabolism.

Body vs. External Supply

🔴 Exogenous (replaces natural)

Brand / Trade Names

No pharmaceutical brand Research chemical only (Not technically a peptide)

Typical Research Dosage

50-100mg/day orally or SubQ. Some protocols use up to 150mg/day.

Vial Duration Guide

50mg vial at 50mg/day = 1 day per vial (usually purchased in bulk). 5mg vials are impractical for standard dosing.

Recommended Vial Size

★ 50mg vials At 50-100mg/day, 5mg vials impractical. 50mg = 1 day per vial. Buy in bulk. No shelf life concern — used immediately.

Time to Effects

EARLY: 2-4 weeks FULL: 8-12 weeks Week 2-4: Subtle increase in energy and metabolic rate. Fat oxidation improvements. Week 4-8: Body composition changes become noticeable, especially when combined with exercise. Week 8-12: Cumulative metabolic benefits. Best results when stacked with exercise and/or GLP-1 agonists. Standalone effects are mild.

Contraindications & Do Not Combine

No strict contraindications with other peptides on this list.

Common Side Effects

Limited data: GI discomfort, nausea (reported anecdotally). No systematic side effect profile established.

Drug Interactions

Unknown — no drug interaction studies

Reversibility

Fully reversible — enzyme inhibition, no feedback loop

Key Peer-Reviewed References

All studies are published in indexed journals unless otherwise noted.

• Neelakantan et al. (2018) BBRC 502(2):349-355 — NNMT inhibition and fat metabolism • Preclinical data only — mouse obesity models • NO HUMAN CLINICAL TRIALS • Small molecule, not a peptide technically

Research Disclaimer

Almost all data is preclinical (animal or in-vitro). No large-scale randomised controlled human trials are available for most compounds on this catalogue. This information is provided for research reference only.

Storage Requirements

Room temp (capsule) | Reconstituted: 2-8°C

State	Condition	Duration
Lyophilised (sealed)	Room temp (capsule) \| Reconstituted: 2-8	12-24 months
Reconstituted	2-8C	4–6 weeks

Reconstitution Note

Reconstitute with bacteriostatic water (BAC water). Do not shake vigorously -- swirl gently to dissolve. Inject BAC water slowly down the side of the vial to avoid denaturing the peptide.

Video Resources

5-Amino-1MQ discussed by researchers & practitioners

Independent educational content from researchers, clinicians, and science communicators. Not affiliated with Pepnerd — provided as supplementary reading.

Educational resources only. The videos above are independent third-party content from researchers, clinicians, and science communicators. Pepnerd is not affiliated with any of these creators and does not endorse or make any claims based on their content. All products are sold strictly for in-vitro scientific research.

Select Vial Size

$55.00 per vial

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Quick Reference

Half-life	~2-3 hours (oral compound)
Delivery	SubQ injection
Typical dose	50-100mg/day
Storage (lyoph.)	Room temp (capsule) \| Reconstituted: 2-8
Storage (recon.)	4–6 weeks
Endogenous?	Exogenous (replaces natural)
Suppression	None known
WADA	Not listed
FDA status	Preclinical only